Matricarin
Matricarin is a sesquiterpene lactone antioxidant with ferric ion reducing antioxidant power activity. Matricarin exhibits free radical scavenging activity. Matricarin induces growth inhibition. Matricarin can be used in the research of ovarian cancer and renal cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 5989-43-5
- 分子式: C17H20O5
- 分子量:304.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
100 μM
Compound: 8
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
|
[PMID: 29122483] |
体外実験
Matricarin is a compound isolated from the leaves of the Artemisia tridentata tridentata subspecies, and its ferric reducing antioxidant activity is 13.22 µM TE/g FW[1].
Matricarin (10-5 M) achieves a growth inhibition rate of up to 89% in OVCAR-3 ovarian cancer cells and a lethality rate of 28% in A498 renal cancer cells, but its overall anti-tumor activity in the NCI-60 cell panel is not significant[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 5989-43-5
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分子量 304.34
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分子式 C17H20O5
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SMILES
CC([C@]1([H])[C@]2([H])[C@@]([C@@H](C(O2)=O)C)([H])[C@H](CC(C)=C13)OC(C)=O)=CC3=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Matricarin
- 5989-43-5
- Biochemical Assay Reagents
- radical-scavenging capacity
- OVCAR-3 ovarian cancer cells
- antioxidant
- ferric reducing antioxidant power
- A498 renal cancer cells
- Artemisia tridentata subsp. tridentata
- renal cancer
- ovarian cancer
- NCI-60 cancer cell line
- sesquiterpene lactone
- Inhibitor
- inhibitor
- inhibit