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Mavrilimumab

(別名: CAM 3001)
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Based on 1 Customer Validation

Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death.

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  • 純度: 98.37%
  • CAS 番号: 1085337-57-0
  • 分子量:143.168 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Mavrilimumab
  • Experimental Validation Results for Mavrilimumab
  • Experimental Validation Results for Mavrilimumab
  • Mavrilimumab Chemical Structure
    Mavrilimumab 構造式
CAS 番号: 1085337-57-0
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 lambda2

  • 1/16

    Loaded Mavrilimumab on AHC2 biosensor, can bind GM-CSF R alpha Protein, Human (HEK293, His, HY-P7783) with an affinity constant of 7.867E-10 M as determined in BLI assay.

  • 1/16

    Flow Cytometry analysis of Hela cells labelling GM-CSFRa (red) with Mavrilimumab (anti-GM-CSFRa) (HY-P99031). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) lambda1(HY-P99987). Black-Unlabelled control, cells without incubation with primary antibody.

  • Mavrilimumab Chemical Structure
    1/16
  • Mavrilimumab
  • Loaded Mavrilimumab on AHC2 biosensor, can bind GM-CSF R alpha Protein, Human (HEK293, His, HY-P7783) with an affinity constant of 7.867E-10 M as determined in BLI assay.
  • Flow Cytometry analysis of Hela cells labelling GM-CSFRa (red) with Mavrilimumab (anti-GM-CSFRa) (HY-P99031). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) lambda1(HY-P99987). Black-Unlabelled control, cells without incubation with primary antibody.
  • Human IgG4 lambda2