MEGA-8
MEGA-8 (N-Octanoyl-N-methylglucamine) is a nonionic sugar-based surfactant. MEGA-8 can gently solubilize membrane proteins without easily causing their denaturation. MEGA-8 is a commonly used reagent for the extraction and study of membrane proteins in biochemistry.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.33%
- CAS 番号: 85316-98-9
- 分子式: C15H31NO6
- 分子量:321.41
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-W040217
MEGA-10Solubilizer -
HY-116285
n-Octyl β-D-glucopyranosideNon-Ionic Detergent -
HY-W015993
Nonyl β-D-glucopyranosideSurfactant -
HY-W142692
Dodecyl β-D-glucopyranosideSurfactant -
HY-W127628
Decyl β-D-glucopyranosideGlucofuran -
HY-W040203
Decyl β-D-maltopyranosideEpithelial Permeability Enhancer -
HY-128974
N-Dodecyl-β-D-maltosideNonionic Detergent -
HY-W127785
N,N-Dimethyldodecylamine N-oxideBiochemical Assay Reagent -
HY-W040216
MEGA-9Non-ionic Surfactant -
HY-W019895
TetradecylphosphocholineDetergent -
HY-W040223
n-Heptyl β-D-thioglucosideBiochemical Assay Reagent -
HY-W127785R
N,N-Dimethyldodecylamine N-oxide (Standard)Biochemical Assay Reagent
生物活性
製品説明
体外実験
MEGA-8 can extract membrane-bound β-aryl ether lyase from Pseudomonas paucimobilis SYK-6 without disrupting its tertiary structure, and it can also detect the activity of β-aryl ether lyase in cell-free lysate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 85316-98-9
-
性状 Solid
-
分子量 321.41
-
分子式 C15H31NO6
-
Color White to off-white
-
SMILES
O[C@@H](CN(C)C(CCCCCCC)=O)[C@@H](O)[C@H](O)[C@H](O)CO
-
別名
N-Octanoyl-N-methylglucamine
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 175 mg/mL (544.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 50 mg/mL (155.56 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Masai E, et al. Detection and localization of a new enzyme catalyzing the beta-aryl ether cleavage in the soil bacterium (Pseudomonas paucimobilis SYK-6). FEBS Lett. 1989;249(2):348-352. [Content Brief]
[2]. Jeffrey GA, et al. The structures of 1-deoxy-(N-methyloctanamido)-D-glucitol (MEGA-8) and 1-deoxy-(N-methylundecanamido)-D-glucitol (MEGA-11). Acta Crystallogr B. 1989;45 ( Pt 4):447-452. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.1113 mL | 15.5565 mL | 31.1129 mL | 77.7823 mL |
| 5 mM | 0.6223 mL | 3.1113 mL | 6.2226 mL | 15.5565 mL | |
| 10 mM | 0.3111 mL | 1.5556 mL | 3.1113 mL | 7.7782 mL | |
| 15 mM | 0.2074 mL | 1.0371 mL | 2.0742 mL | 5.1855 mL | |
| 20 mM | 0.1556 mL | 0.7778 mL | 1.5556 mL | 3.8891 mL | |
| 25 mM | 0.1245 mL | 0.6223 mL | 1.2445 mL | 3.1113 mL | |
| 30 mM | 0.1037 mL | 0.5185 mL | 1.0371 mL | 2.5927 mL | |
| 40 mM | 0.0778 mL | 0.3889 mL | 0.7778 mL | 1.9446 mL | |
| 50 mM | 0.0622 mL | 0.3111 mL | 0.6223 mL | 1.5556 mL | |
| 60 mM | 0.0519 mL | 0.2593 mL | 0.5185 mL | 1.2964 mL | |
| 80 mM | 0.0389 mL | 0.1945 mL | 0.3889 mL | 0.9723 mL | |
| 100 mM | 0.0311 mL | 0.1556 mL | 0.3111 mL | 0.7778 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
MEGA-8 関連分類
HY-W040218 関連分類
Powered by Bioz
Keywords
- MEGA-8
- 85316-98-9
- N-Octanoyl-N-methylglucamine
- MEGA8
- MEGA 8
- Biochemical Assay Reagents
- glucitol chain
- cell-free lysates
- hydrogen-bond chain
- membrane protein crystallization
- orthorhombic crystals
- membrane-associated enzyme
- β-aryl ether cleaving enzyme
- β-hydroxypropiovanillone
- Pseudomonas paucimobilis SYK-6
- Inhibitor
- inhibitor
- inhibit