Miricorilant
Miricorilant (CORT 118335) is a dual selective glucocorticoid (GR) modulator/mineralocorticoid (MR) antagonist. Miricorilant can be used for the research of hypothalamic-pituitary-adrenal (HPA) axis related disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1400902-13-7
- 分子式: C24H23F3N2O2
- 分子量:428.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Glucocorticoid/Mineralocorticoid[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (≈250 g)[1]
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Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg
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Administration:Subcutaneously (s.c.); five days.
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Result:30 mg/kg had lower corticosterone responses relative to 10 mg/kg at 15 and 30 min time points.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1400902-13-7
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分子量 428.45
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分子式 C24H23F3N2O2
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SMILES
O=C1NC(C(CC2=CC=CC(C(F)(F)F)=C2)=C(N1)[C@H]3CC[C@@H](CC3)C4=CC=CC=C4)=O
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別名
CORT 118335
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Miricorilant 関連分類
HY-117965 関連分類
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