Monascorubramine
Based on 1 Customer Validation
Monascorubramine is a metabolite derived from Monascus with antibacterial, cytotoxic and antimitotic activities. Monascorubramine interferes with mitotic spindle tubulin, triggers metaphase mitotic arrest, induces abnormal c‑mitosis division, and exerts antimitotic effects. Monascorubramine exhibits antibacterial activity and inhibits both Gram-positive and Gram-negative bacteria. Monascorubramine can be used in studies related to bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.15%
- CAS 番号: 3627-51-8
- 分子式: C23H27NO4
- 分子量:381.46
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:immortalized human kidney epithelial (IHKE) cells
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Concentration:1 μM; 10 μM; 25 μM
25 μM -
Incubation Time:12 h; 24 h
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Result:Did not induce changes in caspase 3 activity in IHKE cells at any tested concentration or incubation time.
Did not induce formation of apoptotic bodies in IHKE cells at any tested concentration or incubation time.
化学情報
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CAS 番号 3627-51-8
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性状 Solid
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分子量 381.46
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分子式 C23H27NO4
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Color Brown to black
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SMILES
C/C=C/C(NC=C1C2=O)=CC1=CC([C@]23C)=C(C(O3)=O)C(CCCCCCC)=O
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Structure Classification
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Initial Source
Talaromyces amestolkiae
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 7.6 mg/mL (19.92 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6215 mL | 13.1075 mL | 26.2151 mL | 65.5377 mL |
| 5 mM | 0.5243 mL | 2.6215 mL | 5.2430 mL | 13.1075 mL | |
| 10 mM | 0.2622 mL | 1.3108 mL | 2.6215 mL | 6.5538 mL | |
| 15 mM | 0.1748 mL | 0.8738 mL | 1.7477 mL | 4.3692 mL |
Monascorubramine 関連分類
HY-N11071 関連分類
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Keywords
- Monascorubramine
- 3627-51-8
- Endogenous Metabolite
- Bacterial
- Microtubule/Tubulin
- Monascus ruber
- Escherichia coli DHFR
- Monascus purpureus
- Staphylococcus aureus DHFR
- CYP enzymes
- mitotic spindle tubulin
- immortalized human kidney epithelial (IHKE) cells
- Candida albicans DHFR
- Gram-negative bacteria
- Gram-positive bacteria
- Inhibitor
- inhibitor
- inhibit