MRS4596
MRS4596 is a potent and selective P2X4 receptor antagonist with an IC50 value of 1.38 μM for human P2X4 receptor. MRS4596 has neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4596 can be used in research of ischemic stroke .
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2840581-38-4
- 分子式: C22H15N4NaO3S
- 分子量:438.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
P2X Receptor アイソフォーム固有の製品をすべて表示
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生物活性
IC50: 1.38 μM (human P2X4 receptor)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male and female young C57B/6 mice (8-12 weeks; induced transient focal cerebral ischemia by a 60 min right middle cerebral artery occlusion)[1]
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Dosage:5 mg/kg
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Administration:3 days continuous infusion with an Alzet minipump
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Result:Decreased in total hemispheric infarct volume while effects were not significant on cortical or striatal infarct volume alone.
化学情報
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CAS 番号 2840581-38-4
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分子量 438.43
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分子式 C22H15N4NaO3S
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SMILES
O=C(C1)NC(C2=CC=C(C=C2C=C3)C)=C3N(C4=CC=CC(C([N-]5)=NOC5=S)=C4)C1=O.[Na+]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MRS4596 関連分類
HY-151546 関連分類
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