MTSEA hydrobromide
Based on 1 Customer Validation
MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.90%
- CAS 番号: 16599-33-0
- 分子式: C3H10BrNO2S2
- 分子量:236.15
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
154 μM
Compound: ACS 42
|
Antiproliferative activity against human A549 cells after 3 days
Antiproliferative activity against human A549 cells after 3 days
|
[PMID: 18294844] |
| HeLa | IC50 |
198 μM
Compound: ACS 42
|
Inhibition of human HDAC in HeLa cells
Inhibition of human HDAC in HeLa cells
|
[PMID: 18294844] |
Cys modification by MTSEA reduces susceptibility to Cd activation of receptors with A8C or L10C substitutions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 16599-33-0
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性状 Solid
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分子量 236.15
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分子式 C3H10BrNO2S2
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Color White to off-white
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SMILES
CS(=O)(SCCN)=O.Br
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : 50 mg/mL (211.73 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.2346 mL | 21.1730 mL | 42.3460 mL | 105.8649 mL |
| 5 mM | 0.8469 mL | 4.2346 mL | 8.4692 mL | 21.1730 mL | |
| 10 mM | 0.4235 mL | 2.1173 mL | 4.2346 mL | 10.5865 mL | |
| 15 mM | 0.2823 mL | 1.4115 mL | 2.8231 mL | 7.0577 mL | |
| 20 mM | 0.2117 mL | 1.0586 mL | 2.1173 mL | 5.2932 mL | |
| 25 mM | 0.1694 mL | 0.8469 mL | 1.6938 mL | 4.2346 mL | |
| 30 mM | 0.1412 mL | 0.7058 mL | 1.4115 mL | 3.5288 mL | |
| 40 mM | 0.1059 mL | 0.5293 mL | 1.0586 mL | 2.6466 mL | |
| 50 mM | 0.0847 mL | 0.4235 mL | 0.8469 mL | 2.1173 mL | |
| 60 mM | 0.0706 mL | 0.3529 mL | 0.7058 mL | 1.7644 mL | |
| 80 mM | 0.0529 mL | 0.2647 mL | 0.5293 mL | 1.3233 mL | |
| 100 mM | 0.0423 mL | 0.2117 mL | 0.4235 mL | 1.0586 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.