Neritaloside
Based on 1 Customer Validation
Neritaloside could be isolated from nerium oleander. Neritaloside has central nervous system (CNS) depressant effect[2.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97%
- CAS 番号: 465-13-4
- 分子式: C32H48O10
- 分子量:592.72
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
Neritaloside (human tumor cell lines) has antitumor activity with mean IC50 value and mean IC70 value of 0.120 μM and 0.252 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice of NMRI strain (18-22 g) [2
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Dosage:25 mg/kg
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Administration:Intraperitoneal injection; for 6 hours
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Result:Showed sedation in mice at 25 mg/kg dose.
化学情報
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CAS 番号 465-13-4
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性状 Solid
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分子量 592.72
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分子式 C32H48O10
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Color White to off-white
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SMILES
C[C@]([C@](C(CO1)=CC1=O)([H])[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@](C5)([H])[C@@]3(CC[C@@H]5O[C@H](O[C@@H]6C)[C@@H]([C@H]([C@H]6O)OC)O)C)[C@@]4(C2)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Rashan LJ, et, al. Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum. J Ethnopharmacol. 2011 Apr 12;134(3):781-8. [Content Brief]
[2]. Begum S, et, al. Bio-active cardenolides from the leaves of Nerium oleander. Phytochemistry. 1999 Feb;50(3):435-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)