NSC622608
Based on 1 Customer Validation
NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.68%
- CAS 番号: 2593254-90-9
- 分子式: C9H12BrN3OS2
- 分子量:322.25
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
IC50: 4.8 μM (VISTA)[1]
NSC622608 disrupts VISTA-VSIG-3 interaction with an IC50 value of 9.7 ± 0.3 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2593254-90-9
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性状 Solid
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分子量 322.25
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分子式 C9H12BrN3OS2
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Color White to off-white
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SMILES
CN(C)C1=N/C(SS1)=N/CC2=CC=CO2.Br
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 41.67 mg/mL (129.31 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 12.5 mg/mL (38.79 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.1032 mL | 15.5159 mL | 31.0318 mL | 77.5795 mL |
| 5 mM | 0.6206 mL | 3.1032 mL | 6.2064 mL | 15.5159 mL | |
| 10 mM | 0.3103 mL | 1.5516 mL | 3.1032 mL | 7.7580 mL | |
| 15 mM | 0.2069 mL | 1.0344 mL | 2.0688 mL | 5.1720 mL | |
| 20 mM | 0.1552 mL | 0.7758 mL | 1.5516 mL | 3.8790 mL | |
| 25 mM | 0.1241 mL | 0.6206 mL | 1.2413 mL | 3.1032 mL | |
| 30 mM | 0.1034 mL | 0.5172 mL | 1.0344 mL | 2.5860 mL | |
| DMSO | 40 mM | 0.0776 mL | 0.3879 mL | 0.7758 mL | 1.9395 mL |
| 50 mM | 0.0621 mL | 0.3103 mL | 0.6206 mL | 1.5516 mL | |
| 60 mM | 0.0517 mL | 0.2586 mL | 0.5172 mL | 1.2930 mL | |
| 80 mM | 0.0388 mL | 0.1939 mL | 0.3879 mL | 0.9697 mL | |
| 100 mM | 0.0310 mL | 0.1552 mL | 0.3103 mL | 0.7758 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
NSC622608 関連分類
HY-147311 関連分類
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