O4I4
Based on 1 Customer Validation
O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.73%
- CAS 番号: 412008-21-0
- 分子式: C15H20N2S
- 分子量:260.40
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
0.26 μM
Compound: 19
|
Displacement of [125I]TARC from CCR4 expressed in human CEM cell line
Displacement of [125I]TARC from CCR4 expressed in human CEM cell line
|
[PMID: 16497499] |
| HFF | IC50 |
>20 μM
Compound: 23; O4, O4I4
|
Cytotoxicity against human HFF cells assessed as inhibition of cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human HFF cells assessed as inhibition of cell viability measured after 48 hrs by MTT assay
|
[PMID: 37253308] |
| NCCIT | IC50 |
10.94 μM
Compound: 23; O4, O4I4
|
Cytotoxicity against human NCCIT cells assessed as inhibition of cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human NCCIT cells assessed as inhibition of cell viability measured after 48 hrs by MTT assay
|
[PMID: 37253308] |
化学情報
-
CAS 番号 412008-21-0
-
性状 Solid
-
分子量 260.40
-
分子式 C15H20N2S
-
Color White to off-white
-
SMILES
CC1=C(C(NC2=NC(C(C)(C)C)=CS2)=CC=C1)C
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 250 mg/mL (960.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8402 mL | 19.2012 mL | 38.4025 mL | 96.0061 mL |
| 5 mM | 0.7680 mL | 3.8402 mL | 7.6805 mL | 19.2012 mL | |
| 10 mM | 0.3840 mL | 1.9201 mL | 3.8402 mL | 9.6006 mL | |
| 15 mM | 0.2560 mL | 1.2801 mL | 2.5602 mL | 6.4004 mL | |
| 20 mM | 0.1920 mL | 0.9601 mL | 1.9201 mL | 4.8003 mL | |
| 25 mM | 0.1536 mL | 0.7680 mL | 1.5361 mL | 3.8402 mL | |
| 30 mM | 0.1280 mL | 0.6400 mL | 1.2801 mL | 3.2002 mL | |
| 40 mM | 0.0960 mL | 0.4800 mL | 0.9601 mL | 2.4002 mL | |
| 50 mM | 0.0768 mL | 0.3840 mL | 0.7680 mL | 1.9201 mL | |
| 60 mM | 0.0640 mL | 0.3200 mL | 0.6400 mL | 1.6001 mL | |
| 80 mM | 0.0480 mL | 0.2400 mL | 0.4800 mL | 1.2001 mL | |
| 100 mM | 0.0384 mL | 0.1920 mL | 0.3840 mL | 0.9601 mL |
O4I4 関連分類
HY-155528 関連分類
Powered by Bioz