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Omoprubart

(別名: CAN-106)
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Based on 1 Customer Validation

Omoprubart is an anti-C5 complement recombinant humanized monoclonal antibody. Omolubat can prevent C5 from cleaving into C5a and C5b, thereby inhibiting the formation and activation of the C5b-dependent membrane attack complex (MAC) on the surface of susceptible cells, leading to cell lysis (destruction). Omoprubart can be used for the study of paroxysmal nocturnal hemoglobinuria (PNH).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 97.769%
  • CAS 番号: 2763342-87-4
  • 分子量:145.657 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Omoprubart
  • Experimental Validation Results for Omoprubart
  • Experimental Validation Results for Omoprubart
  • Omoprubart Chemical Structure
    Omoprubart 構造式
CAS 番号: 2763342-87-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    IgG2-G4-kappa

  • 1/16

    Immobilized Complement C5 Protein, Human (HEK293, His, HY-P73396) can bind Omoprubart. The EC50 for this effect is 3.473 ng/mL.

  • 1/16

    Flow Cytometry analysis of HepG2 cells with Omoprubart (HY-P990753, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa(HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Omoprubart Chemical Structure
    1/16
  • Omoprubart
  • Immobilized Complement C5 Protein, Human (HEK293, His, HY-P73396) can bind Omoprubart. The EC50 for this effect is 3.473 ng/mL.
  • Flow Cytometry analysis of HepG2 cells with Omoprubart (HY-P990753, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa(HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG2-G4-kappa