Perrimustine
Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia.
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- CAS 番号: 96413-13-7
- 分子式: C6H12ClN3O3S
- 分子量:241.70
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 96413-13-7
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分子量 241.70
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分子式 C6H12ClN3O3S
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SMILES
CS(CCNC(N(N=O)CCCl)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Kim-Triana B, et al. Phase I trial of Perrimustine, a new cysteamine (2-chloroethyl) nitrosourea: an intrapatient escalation scheme. Anticancer Drugs. 1992 Jun;3(3):225-31. [Content Brief]
[2]. Godeneche D, et al. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells. Cancer Res. 1990 Sep 15;50(18):5898-903. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)