PG 34
Based on 1 Customer Validation
PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 (HY-119738).
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- 純度: 98.0%
- CAS 番号: 1681056-62-1
- 分子式: C28H25N3O5S2
- 分子量:547.65
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
PG34 (0.5-50 μM; 24 h) shows no detectable inhibition of OGT in CHO cells, displays no effect on apoptotic signaling, and shows a moderate effect on cell viability only at the highest concentration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CHO cells
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Concentration:0.5-50 µM
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Incubation Time:24 hours
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Result:Inhibited cell growth moderately at 50 µM.
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Cell Line:CHO cells
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Concentration:10, 25, and 50 µM
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Incubation Time:24 hours
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Result:Showed no reduction in global O-GlcNAcylation in cells.
化学情報
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CAS 番号 1681056-62-1
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性状 Solid
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分子量 547.65
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分子式 C28H25N3O5S2
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Color White to off-white
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SMILES
O=C(N1)C=CC2=C1C=CC(S(N[C@H](CC3=CC=CC=C3)C(N(CC4=CC=CO4)CC5=CC=CS5)=O)(=O)=O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 100 mg/mL (182.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (290 KB)
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SDS (393 KB)
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- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8260 mL | 9.1299 mL | 18.2598 mL | 45.6496 mL |
| 5 mM | 0.3652 mL | 1.8260 mL | 3.6520 mL | 9.1299 mL | |
| 10 mM | 0.1826 mL | 0.9130 mL | 1.8260 mL | 4.5650 mL | |
| 15 mM | 0.1217 mL | 0.6087 mL | 1.2173 mL | 3.0433 mL | |
| 20 mM | 0.0913 mL | 0.4565 mL | 0.9130 mL | 2.2825 mL | |
| 25 mM | 0.0730 mL | 0.3652 mL | 0.7304 mL | 1.8260 mL | |
| 30 mM | 0.0609 mL | 0.3043 mL | 0.6087 mL | 1.5217 mL | |
| 40 mM | 0.0456 mL | 0.2282 mL | 0.4565 mL | 1.1412 mL | |
| 50 mM | 0.0365 mL | 0.1826 mL | 0.3652 mL | 0.9130 mL | |
| 60 mM | 0.0304 mL | 0.1522 mL | 0.3043 mL | 0.7608 mL | |
| 80 mM | 0.0228 mL | 0.1141 mL | 0.2282 mL | 0.5706 mL | |
| 100 mM | 0.0183 mL | 0.0913 mL | 0.1826 mL | 0.4565 mL |
PG 34 関連分類
HY-148113 関連分類
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