[Phe2]-TRH
[Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin.
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- CAS 番号: 34783-35-2
- 分子式: C19H24N4O4
- 分子量:372.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
![[Phe2]-TRH Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p3962.gif "Click to View [Phe2]-TRH Chemical Structure")
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
[Phe2]-TRH has a lower affinity for the TRH receptor than TRH itself, and the substitution of azPro for Pro in the [Phe2, azPro3]-TRH analogue causes an approximately 200-fold further loss in affinity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 34783-35-2
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分子量 372.42
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分子式 C19H24N4O4
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シーケンスの短縮
Glp-FP-NH2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Eckle E, et al. Conformational properties of central nervous system active thyrotropin releasing hormone analogues: probing structure-activity relationships at the molecular level. J Med Chem. 1985 Jan;28(1):125-37. [Content Brief]
[2]. Zhang WJ, et al. Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues. J Am Chem Soc. 2003 Feb 5;125(5):1221-35. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
[Phe2]-TRH 関連分類
HY-P3962 関連分類
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