Phenaglycodol
Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 79-93-6
- 分子式: C11H15ClO2
- 分子量:214.69
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Phenaglycodol (55-80 mg/kg, i.p., 1 time) has antiepileptic activity in mice[1].
Phenaglycodol (50-100 mg/kg, i.g., 1 time) has antiepileptic activity in monkey[1].
Phenaglycodol (130mg/kg, i.p., 1 time) lowers the concentration of Meprobamate in serum and brain[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Cat[1]
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Dosage:20 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed that cat became quiet.
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Animal Model:Monkey[1]
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Dosage:50-100 mg/kg
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Administration:Intragastric Gavage (i.g.)
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Result:Showed that monkey became less aggressive or less fearful.
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Animal Model:Mice[1]
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Dosage:55-80 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed a reduction in spontaneous activity and sit quietly.
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Animal Model:Female Rats(Sprague-Dawley, 170g)[2]
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Dosage:130 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed that the decrease of Meprobamate concentration in the serum and brain of the pretrealed rats was more rapid than that in control rats.
化学情報
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CAS 番号 79-93-6
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分子量 214.69
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分子式 C11H15ClO2
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SMILES
ClC1=CC=C(C(C)(C(C)(C)O)O)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31. [Content Brief]
[2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Phenaglycodol 関連分類
HY-105845 関連分類
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