Phenanthrene-d10
Based on 1 Customer Validation
Phenanthrene-d10 is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices. Phenanthrene induces oxidative stress and inflammation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.46%
- CAS 番号: 1517-22-2
- 分子式: C14D10
- 分子量:188.30
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1517-22-2
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非標識Cas 85-01-8
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性状 Solid
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分子量 188.30
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分子式 C14D10
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Color White to off-white
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SMILES
[2H]C1=C([2H])C2=C([2H])C([2H])=C([2H])C([2H])=C2C3=C([2H])C([2H])=C([2H])C([2H])=C13
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別名
フェナントレン-d10
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (531.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Sun K, et al. Subcellular distribution and biotransformation of phenanthrene in pakchoi after inoculation with endophytic Pseudomonas sp. as probed using HRMS coupled with isotope-labeling. Environ Pollut. 2018 Jun;237:858-867.;Dupuy J, et al. Effect and localization of phenanthrene in maize roots. Chemosphere. 2016 Apr;149:130-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3107 mL | 26.5534 mL | 53.1067 mL | 132.7669 mL |
| 5 mM | 1.0621 mL | 5.3107 mL | 10.6213 mL | 26.5534 mL | |
| 10 mM | 0.5311 mL | 2.6553 mL | 5.3107 mL | 13.2767 mL | |
| 15 mM | 0.3540 mL | 1.7702 mL | 3.5404 mL | 8.8511 mL | |
| 20 mM | 0.2655 mL | 1.3277 mL | 2.6553 mL | 6.6383 mL | |
| 25 mM | 0.2124 mL | 1.0621 mL | 2.1243 mL | 5.3107 mL | |
| 30 mM | 0.1770 mL | 0.8851 mL | 1.7702 mL | 4.4256 mL | |
| 40 mM | 0.1328 mL | 0.6638 mL | 1.3277 mL | 3.3192 mL | |
| 50 mM | 0.1062 mL | 0.5311 mL | 1.0621 mL | 2.6553 mL | |
| 60 mM | 0.0885 mL | 0.4426 mL | 0.8851 mL | 2.2128 mL | |
| 80 mM | 0.0664 mL | 0.3319 mL | 0.6638 mL | 1.6596 mL | |
| 100 mM | 0.0531 mL | 0.2655 mL | 0.5311 mL | 1.3277 mL |