Phospholipase D, cabbage
Phospholipase D, cabbage is a phospholipase D of the PLD superfamily found in cabbage, acting as a phosphodiesterase and signaling enzyme with activity toward phosphatidylcholine. Phospholipase D hydrolyzes phosphatidylcholine to phosphatidic acid and choline, and catalyzes transphosphatidylation reactions. Phospholipase D can be used for the research of myocardial disease, ischemic heart disease, congestive heart failure, diabetic cardiomyopathy, cardiac hypertrophy, vascular abnormalities, breast cancer, gastric cancer, renal cancer, colorectal cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 9001-87-0
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
Cabbage phospholipase D exhibits substrate specificity, and it does not hydrolyze rac. 1,2-diacylglycerol-3-phosphocholine with a 2-alkyl substitution at the sn-2 position[1].
Phospholipase D, cabbage is soluble at pH 5.6.
Phospholipase D hydrolyzes choline phospholipids to quantify the incorporation of propargylcholine[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 9001-87-0
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SMILES
[Phospholipase D, cabbage]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Shukla SD, Halenda SP. Phospholipase D in cell signalling and its relationship to phospholipase C. Life sciences. 1991;48(9):851-66. [Content Brief]
[2]. Selvy PE, et al. Phospholipase D: enzymology, functionality, and chemical modulation. Chem Rev. 2011 Oct 12;111(10):6064-119. [Content Brief]
[3]. Jao CY, Roth M, Welti R, et al.. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2009 Sep 08;106(36):15332-7. [Content Brief]
[4]. Tappia PS, et al. Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med. 2006 Aug 1;41(3):349-61. [Content Brief]
[5]. Foster DA, Xu L. Phospholipase D in cell proliferation and cancer. Mol Cancer Res. 2003 Sep;1(11):789-800. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Phospholipase D, cabbage 関連分類
HY-P2812B 関連分類
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