Plinabulin-d1
Plinabulin-d1 is an active compound.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2054938-28-0
- 分子式: C19H19DN4O2
- 分子量:337.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
2.5 nM
Compound: MBRI-001
|
Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 30910474] |
| Jurkat | IC50 |
4.3 nM
Compound: 9
|
Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay
|
[PMID: 28228362] |
| NCI-H1975 | IC50 |
9.3 nM
Compound: MBRI-001
|
Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 30910474] |
| NCI-H446 | IC50 |
22 nM
Compound: 9
|
Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay
|
[PMID: 28228362] |
| NCI-H460 | IC50 |
33.2 nM
Compound: 9
|
Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay
|
[PMID: 28228362] |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2054938-28-0
-
非標識Cas 714272-27-2
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分子量 337.39
-
分子式 C19H19DN4O2
-
SMILES
CC(C)(C)C(N=CN1)=C1/C([2H])=C2C(N/C(C(N/2)=O)=C\C3=CC=CC=C3)=O
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別名
NPI-2358-d1
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)