Polyvinylimidazole
Based on 1 Customer Validation
Polyvinylimidazole (Vimdemer) is an antibacterial polymer and membrane modifier. Polyvinylimidazole can form anticancer complexes with Cadmium chloride. Polyvinylimidazole disrupts bacterial membrane structures through electrostatic and hydrophobic interactions, inhibits bacterial adhesion and biofilm formation, thereby reducing membrane surface biofouling and enhancing the water flux recovery rate after fouling-cleaning cycles. Polyvinylimidazole exhibits broad-spectrum but selective antibacterial activity, inhibiting fungi and bacteria. Polyvinylimidazole can modify PVDF membranes, and the modified membranes inhibit bacteria in a concentration-dependent manner. Polyvinylimidazole can be used in research related to cancer, fungal and bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 25232-42-2
- 分子式: (C5H6N2)x
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
体外実験
Polyvinylimidazole (5-15% w/v) modified membranes inhibit E. coli and S. aureus in a concentration-dependent manner[2].
After loading with polyvinylimidazole (5-15% w/v; 107 CFU/mL bacteria; 3 h filtration; before and after cleaning), the live cell area of E. coli and S. aureus on the membrane surface after dynamic fouling decreases, while the dead cell area increases, with the M15 membrane showing the lowest residual live cell area[2].
Polyvinylimidazole (5-15% w/v; 3 h) modified membranes cause structural disruption of adhered E. coli and S. aureus[2].
Polyvinylimidazole (0.5-2 mg/mL; 1-24 h) kills Kloeckera apiculata and Candida albicans, and inhibits all tested bacteria and fungi in plate count assays[3].
Polyvinylimidazole modifies the PVDF membrane, gradually reducing the pore size, porosity, and roughness while increasing the positive zeta potential[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Kloeckera apiculata, Candida albicans, Escherichia coli, Salmonella enteritidis and Staphylococcus aureus
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Concentration:0.5, 1 and 2 mg/mL
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Incubation Time:1, 12 and 24
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Result:Both types of yeast died completely in 1 mg/mL concentration of this compound during 12-24 h treatments.
Exhibited antimicrobial activity against Escherichia coli, Salmonella enteritidis and Staphylococcus aureus.
Weaker activity was shown againstAspergillius niger and Penicillium roqueforti.
化学情報
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CAS 番号 25232-42-2
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性状 Solid
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分子式 (C5H6N2)x
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Color White to light yellow
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SMILES
CC(CC)N1C=NC=C1.[n]
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別名
Vimdemer
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
純度とドキュメンテーション
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データシート (288 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)