PPA
Based on 1 Customer Validation
PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.01%
- CAS 番号: 452072-22-9
- 分子式: C10H13NO2S2
- 分子量:243.35
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
IC50 & Target
|
Disulfide Cleavable Linker |
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 452072-22-9
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性状 Solid
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分子量 243.35
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分子式 C10H13NO2S2
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Color Light yellow to yellow
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SMILES
CC(SSC1=NC=CC=C1)CCC(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (410.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1093 mL | 20.5463 mL | 41.0926 mL | 102.7314 mL |
| 5 mM | 0.8219 mL | 4.1093 mL | 8.2185 mL | 20.5463 mL | |
| 10 mM | 0.4109 mL | 2.0546 mL | 4.1093 mL | 10.2731 mL | |
| 15 mM | 0.2740 mL | 1.3698 mL | 2.7395 mL | 6.8488 mL | |
| 20 mM | 0.2055 mL | 1.0273 mL | 2.0546 mL | 5.1366 mL | |
| 25 mM | 0.1644 mL | 0.8219 mL | 1.6437 mL | 4.1093 mL | |
| 30 mM | 0.1370 mL | 0.6849 mL | 1.3698 mL | 3.4244 mL | |
| 40 mM | 0.1027 mL | 0.5137 mL | 1.0273 mL | 2.5683 mL | |
| 50 mM | 0.0822 mL | 0.4109 mL | 0.8219 mL | 2.0546 mL | |
| 60 mM | 0.0685 mL | 0.3424 mL | 0.6849 mL | 1.7122 mL | |
| 80 mM | 0.0514 mL | 0.2568 mL | 0.5137 mL | 1.2841 mL | |
| 100 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 1.0273 mL |