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製品番号: HY-N13355

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Przewaquinone B

Name: Przewaquinone B
Brand: MedChemExpress
SKU: HY-N13355
Price: 600.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Przewaquinone B is an abietane-type diterpene quinone (tanshinone) and a diterpenoid compound. Przewaquinone B can be isolated from the rhizomes of Salvia miltiorrhiza Bunge, the roots of Salvia przewarskii, and the roots of Salvia constanea. Przewaquinone B exhibits antitumor activity against cervical cancer and promyelocytic leukemia. Przewaquinone B can be used in research related to cervical cancer and promyelocytic leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 76829-01-1
分子式: C₁₈H₁₂O₄
分子量:292.29

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Przewaquinone B 構造式

CAS 番号: 76829-01-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	3.22 μM Compound: 6	Antiproliferative activity against human KB cells after 72 hrs by sulforhodamine B assay Antiproliferative activity against human KB cells after 72 hrs by sulforhodamine B assay	[PMID: 29294282]
HeLa	IC50	19.0 μM	Cytotoxicity against human cervical cancer HeLa cells. Cytotoxicity against human cervical cancer HeLa cells.	27032190
HL-60	IC50	3.0 μM	Cytotoxicity against human promyelocytic leukemia HL-60 cells. Cytotoxicity against human promyelocytic leukemia HL-60 cells.	27032190

体外実験

Przewaquinone B exhibits weak cytotoxicity against HeLa cells (IC₅₀ = 19.0 μM) and significant cytotoxicity against HL-60 cells (IC₅₀ = 3.0 μM)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 76829-01-1
分子量 292.29
分子式 C₁₈H₁₂O₄
SMILES

O=C1C(C2=C(C3=C1C(C=CC=C4C)=C4C=C3)OC=C2CO)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Wang X, et al. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med Res Rev. 2007 Jan;27(1):133-48. [Content Brief]

[2]. Tsukada H, et al. Two New Diterpenoids from Salvia przewarskii. Natural product communications. 2016 Feb;11(2):159-61. [Content Brief]

[3]. YANG M H, et al. Diterpenoids from Salvia species[J]. Pharmacy and Pharmacology Communications, 1996, 2(1): 69-71.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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