RdRP-IN-2
Based on 1 Customer Validation
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. RdRP-IN-2 significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 μM.RdRP-IN-2 also inhibits Feline coronavirus (FIPV) replication.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.01%
- CAS 番号: 2863657-16-1
- 分子式: C33H30N2O5S
- 分子量:566.67
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
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RNA Polymerase |
RdRP-IN-2 (Compound 17) completely inhibits the replication of both SARS-CoV-2 and Feline coronavirus (FIPV). RdRP-IN-2 is not cytotoxic for Vero and CRFK cells[1].
RdRP-IN-2 (Compound 17) shows anti-SARS-CoV-2 activities with an EC50 value of 527.3 nM in Vero cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2863657-16-1
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性状 Solid
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分子量 566.67
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分子式 C33H30N2O5S
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Color Light yellow to green yellow
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SMILES
O=C(O)[C@H](CC1=CC=CC=C1)NC(C(C=C2C3=CC=CC=C3)=C(SC4=CC=C(OC5CCCCC5)C=C46)N6C2=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (176.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (254 KB)
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- Français - FR (254 KB)
- Deutsch - DE (254 KB)
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- Español - ES (254 KB)
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- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7647 mL | 8.8235 mL | 17.6470 mL | 44.1174 mL |
| 5 mM | 0.3529 mL | 1.7647 mL | 3.5294 mL | 8.8235 mL | |
| 10 mM | 0.1765 mL | 0.8823 mL | 1.7647 mL | 4.4117 mL | |
| 15 mM | 0.1176 mL | 0.5882 mL | 1.1765 mL | 2.9412 mL | |
| 20 mM | 0.0882 mL | 0.4412 mL | 0.8823 mL | 2.2059 mL | |
| 25 mM | 0.0706 mL | 0.3529 mL | 0.7059 mL | 1.7647 mL | |
| 30 mM | 0.0588 mL | 0.2941 mL | 0.5882 mL | 1.4706 mL | |
| 40 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1029 mL | |
| 50 mM | 0.0353 mL | 0.1765 mL | 0.3529 mL | 0.8823 mL | |
| 60 mM | 0.0294 mL | 0.1471 mL | 0.2941 mL | 0.7353 mL | |
| 80 mM | 0.0221 mL | 0.1103 mL | 0.2206 mL | 0.5515 mL | |
| 100 mM | 0.0176 mL | 0.0882 mL | 0.1765 mL | 0.4412 mL |
RdRP-IN-2 関連分類
HY-139442 関連分類
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