RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2665669-32-7
- 分子式: C21H16ClN3O2S2
- 分子量:441.95
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
RIPK3-IN-2 (0.3-20 μM; 42 h) inhibits HT-29 cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 14 h) inhibits MEF cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 18 h) inhibits L929 cell growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HT-29 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:42 hours
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Result:Showed EC50 value of 0.085 μM.
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Cell Line:MEF cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:14 hours
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Result:Showed EC50 value of 0.24 μM.
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Cell Line:L929 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:18 hours
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Result:Showed EC50 value of 0.21 μM.
化学情報
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CAS 番号 2665669-32-7
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分子量 441.95
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分子式 C21H16ClN3O2S2
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SMILES
O=S1(C=C(C2CC2)C3=C1C=C4C(NC5=CC6=C(SC=N6)C=C5)=CC=NC4=C3)=O.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)