RM1490
RM1490 (Compound 251) acts as an inhibitor of μ-opioid receptor (MOR) (IC50 ≤ 300 nM), an activator of δ-opioid receptor (DOR) (EC50 > 3000 nM), and an inhibitor of κ-opioid receptor (KOR) (IC50 ≤ 300 nM). RM1490 is applicable to the research of neuropsychiatric disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2849392-47-6
- 分子式: C25H34N2O2
- 分子量:394.55
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Opioid Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
|
μ Opioid Receptor/MOR ≤ 300 nM (IC50) |
δ Opioid Receptor/DOR > 3000 nM (EC50) |
κ Opioid Receptor/KOR ≤ 300 nM (IC50) |
RM1490 (Compound 251) (Serially diluted concentrations; 15 minutes at 37°C, 5% CO2 plus 15 minutes at room temperature) potently antagonizes the mu opioid receptor in CHO Tag-lite human mOR stable cells with an IC50 ≤ 300 nM[1].
RM1490 (Compound 251) acts as a weak agonist of the delta opioid receptor with an EC50 > 3000 nM[1].
RM1490 (Compound 251) potently antagonizes kappa opioid receptor β-arrestin signaling with an IC50 ≤ 300 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2849392-47-6
-
分子量 394.55
-
分子式 C25H34N2O2
-
SMILES
CC(C=C(C=C1C)O)=C1C[C@H](N(C)C)CNC(C[C@H](C2=CC=CC=C2)C3CC3)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RM1490 関連分類
HY-182453 関連分類
Powered by Bioz