RO5192022
RO5192022 is a TAAR1 agonist and a radioligand for TAAR1 binding assays. RO5192022 exhibits antipsychotic-like properties. RO5192022 can be used in studies related to schizophrenia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1043489-40-2
- 分子式: C9H8F2N2O
- 分子量:198.17
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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TAAR1 |
TAAR1 is a trace amine-sensing GPCR enriched in the central nervous system. It regulates dopamine and serotonin monoamine neural circuits, and serves as a therapeutic target for schizophrenia, depression and drug addiction.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1043489-40-2
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分子量 198.17
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分子式 C9H8F2N2O
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SMILES
NC1=N[C@H](CO1)C2=CC=C(C=C2F)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Revel FG, et al.. TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America. 2011 May 17;108(20):8485-90. [Content Brief]
[2]. Aleksandrov AA, et al.. The TAAR5 agonist α-NETA causes dyskinesia in mice. Neuroscience letters. 2019 Jun 21;704:208-211. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RO5192022 関連分類
HY-186230 関連分類
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