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製品番号: HY-N8400

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Roridin L2

Name: Roridin L2
Brand: MedChemExpress
SKU: HY-N8400
Price: 370.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Roridin L2 is an inhibitor of the peptidyl transferase center of the 60S ribosomal subunit. Roridin L2 irreversibly binds to this center and inhibits protein biosynthesis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度 : 99.9%
CAS 番号: 85124-22-7
分子式: C₂₉H₃₈O₉
分子量:530.61

保管条件:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Roridin L2 構造式

CAS 番号: 85124-22-7

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Roridin L2 is an inhibitor of the peptidyl transferase center of the 60S ribosomal subunit. Roridin L2 irreversibly binds to this center and inhibits protein biosynthesis^[1]^[2].

体外実験

Roridin L2 (0-50 μM; 24 h) decreases viability of NuLi-1 cells and THP-1 macrophages with an IC₅₀ in the lower μM range^[2].
Roridin L2 (up to 1000 ng/mL; 48 h) is non-cytotoxic and does not induce apoptosis or DNA fragmentation in PC-12 neuronal cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Cell Viability Assay^[2]

View Protocol

Cell Line:

human bronchial epithelial NuLi-1 cells and THP-1 macrophages
Concentration:

0 to 50 μM
Incubation Time:

24 h
Result:

Showed an IC₅₀ in the lower μM range.

化学情報

CAS 番号 85124-22-7
性状 Crystal
分子量 530.61
分子式 C₂₉H₃₈O₉
Color Off-white to light yellow
SMILES

CC1=C[C@@]2([C@](CO)(CC1)[C@@]3([C@]4([C@]([H])(O2)C[C@H]3OC(/C=C\C=C\C(C(C)O)OCCC5=CC(OC5)=O)=O)OC4)C)[H]
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Stachybotrys chartarum
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (284 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Islam Z, et al. Purification and comparative neurotoxicity of the trichothecenes satratoxin G and roridin L2 from Stachybotrys chartarum. Journal of Toxicology and Environmental Health, Part A. 2009 Sep 16;72(20):1242-51. [Content Brief]

[2]. Wolff A, et al. Establishment of a Human Cell-Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold. Environmental toxicology. 2026 Jul 22.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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