RYL-552
Based on 1 Customer Validation
RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.09%
- CAS 番号: 1801444-56-3
- 分子式: C24H17F4NO2
- 分子量:427.39
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh7.5.1 | CC50 |
>10 μM
Compound: 2; RYL-552
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Cytotoxicity against human Huh7.5.1 cells assessed as decrease in cell viability after 48 hrs by WST1 assay
Cytotoxicity against human Huh7.5.1 cells assessed as decrease in cell viability after 48 hrs by WST1 assay
|
[PMID: 30938999] |
化学情報
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CAS 番号 1801444-56-3
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性状 Solid
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分子量 427.39
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分子式 C24H17F4NO2
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Color White to off-white
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SMILES
O=C1C(C)=C(NC2=C1C(F)=CC=C2)C3=CC=C(C=C3)CC4=CC=C(C=C4)OC(F)(F)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (116.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3398 mL | 11.6989 mL | 23.3978 mL | 58.4946 mL |
| 5 mM | 0.4680 mL | 2.3398 mL | 4.6796 mL | 11.6989 mL | |
| 10 mM | 0.2340 mL | 1.1699 mL | 2.3398 mL | 5.8495 mL | |
| 15 mM | 0.1560 mL | 0.7799 mL | 1.5599 mL | 3.8996 mL | |
| 20 mM | 0.1170 mL | 0.5849 mL | 1.1699 mL | 2.9247 mL | |
| 25 mM | 0.0936 mL | 0.4680 mL | 0.9359 mL | 2.3398 mL | |
| 30 mM | 0.0780 mL | 0.3900 mL | 0.7799 mL | 1.9498 mL | |
| 40 mM | 0.0585 mL | 0.2925 mL | 0.5849 mL | 1.4624 mL | |
| 50 mM | 0.0468 mL | 0.2340 mL | 0.4680 mL | 1.1699 mL | |
| 60 mM | 0.0390 mL | 0.1950 mL | 0.3900 mL | 0.9749 mL | |
| 80 mM | 0.0292 mL | 0.1462 mL | 0.2925 mL | 0.7312 mL | |
| 100 mM | 0.0234 mL | 0.1170 mL | 0.2340 mL | 0.5849 mL |
RYL-552 関連分類
HY-120338 関連分類
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