SAG-524
Based on 1 Customer Validation
SAG-524 is a potent oral small molecule HBV viral replication inhibitor. SAG-524 decreased HBV-DNA and HbsAg levels in supernatant of HepG2.2.15 cells, IC50 0.92 and 1.4 nM, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.50%
- CAS 番号: 2246696-89-7
- 分子式: C30H32ClN5O4S
- 分子量:594.12
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
生物活性
製品説明
化学情報
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CAS 番号 2246696-89-7
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性状 Solid
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分子量 594.12
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分子式 C30H32ClN5O4S
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Color Light yellow to yellow
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SMILES
COCCN1CCN(CC1)C2=NC3=CC=C(C=C3S2)N4C=C(C(C=C4C5=CC(Cl)=C(C=C5)N6CCCC6)=O)C(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (168.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6832 mL | 8.4158 mL | 16.8316 mL | 42.0790 mL |
| 5 mM | 0.3366 mL | 1.6832 mL | 3.3663 mL | 8.4158 mL | |
| 10 mM | 0.1683 mL | 0.8416 mL | 1.6832 mL | 4.2079 mL | |
| 15 mM | 0.1122 mL | 0.5611 mL | 1.1221 mL | 2.8053 mL | |
| 20 mM | 0.0842 mL | 0.4208 mL | 0.8416 mL | 2.1040 mL | |
| 25 mM | 0.0673 mL | 0.3366 mL | 0.6733 mL | 1.6832 mL | |
| 30 mM | 0.0561 mL | 0.2805 mL | 0.5611 mL | 1.4026 mL | |
| 40 mM | 0.0421 mL | 0.2104 mL | 0.4208 mL | 1.0520 mL | |
| 50 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8416 mL | |
| 60 mM | 0.0281 mL | 0.1403 mL | 0.2805 mL | 0.7013 mL | |
| 80 mM | 0.0210 mL | 0.1052 mL | 0.2104 mL | 0.5260 mL | |
| 100 mM | 0.0168 mL | 0.0842 mL | 0.1683 mL | 0.4208 mL |