2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

製品番号: HY-175552
Target:  

Tau Protein

研究分野:  

Neurological Disease

CHIPOpt, a peptide, is an orthosteric CHIP TPR domain inhibitor with a Kd of ∼16 nM. CHIPOpt has anti-aggregation activity and decreases p.tau ubiquitination with little effect on unmodified tau. CHIPOpt can be used for Alzheimer’s disease research .
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製品番号: HY-B0754
CAS 番号: 14459-29-1
別名: Hematoporphyrin IX
Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light .
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製品番号: HY-B1348R
CAS 番号: 695-53-4
Dimethadione (Standard) is the analytical standard of Dimethadione. This product is intended for research and analytical applications. Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal[1].
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製品番号: HY-N1427R
CAS 番号: 16409-34-0
別名: Sodium glycyldeoxycholate (Standard)
Glycodeoxycholate (Sodium) (Standard) is the analytical standard of Glycodeoxycholate (Sodium). This product is intended for research and analytical applications. Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels[1][2][3].
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製品番号: HY-W013816
CAS 番号: 131-18-0
Target:  

AMPK Akt

研究分野:  

Metabolic Disease

Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant .
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製品番号: HY-100426A
CAS 番号: 137275-80-0
別名: MKC242
Target:  

5-HT Receptor

研究分野:  

Neurological Disease

Osemozotan hydrochloride (MKC242) is a selective 5-HT1A receptor agonist. Osemozotan hydrochloride decreases the number of c-Fos-positive cells caused by MAMP in mice. Osemozotan hydrochloride can be used for the research of depressive disorder .
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製品番号: HY-108499
CAS 番号: 199522-35-5
純度:  99.3%
研究分野:  

Neurological Disease

NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning .
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製品番号: HY-114813
CAS 番号: 1497249-95-2
KHG26693 is a thiazole derivative with anti-inflammatory and antioxidant properties. KHG26693 normalizes disturbed glucose metabolism by enhancing glucose utilization and decreasing liver glucose production via insulin release. KHG26693 is promising for research of diabetes .
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製品番号: HY-119064
CAS 番号: 85493-98-7
研究分野:  

Neurological Disease

L-645164 is a potent inhibitor of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase. L-645164 produces substantial decreases in circulating serum cholesterol concentrations in dogs. L-645164 is promising for research of central nervous system disorders .
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製品番号: HY-122464B
CAS 番号: 62653-85-4
別名: 2-iso Jasmonic acid; 7-iso Jasmonic acid
研究分野:  

Others

7-epi Jasmonic acid is the isomer of (±)-Jasmonic acid (HY-122464). (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
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製品番号: HY-13664R
CAS 番号: 1492-18-8
別名: Leucovorin calcium (Standard); Calcium folinate (Standard)
Folinic acid (calcium) (Standard) is the analytical standard of Folinic acid (calcium). This product is intended for research and analytical applications. Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
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製品番号: HY-147371
CAS 番号: 115618-99-0
Target:  

Parasite

研究分野:  

Infection Neurological Disease

Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC50 value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrP S c levels - .
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製品番号: HY-148610
CAS 番号: 893739-96-3
Target:  

Others

研究分野:  

Metabolic Disease

LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1) .
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製品番号: HY-153986
CAS 番号: 2565572-83-8
純度:  99.13%
Target:  

Cathepsin

研究分野:  

Neurological Disease

AEP-IN-2 is an asparagine endopeptidase (AEP) inhibitor via block AEP cleavage of APP and Tau. AEP-IN-2 has oral activity and decreases Aβ40 and Aβ42 and p-Tau levels .
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製品番号: HY-155716
CAS 番号: 2702262-15-3
研究分野:  

Infection

G43-C3-TEG is a glycosyl-transferase inhibitor. G43-C3-TEG reduces the biofilm formation by decreasing the production of EPS (extracellular polysaccharides) .
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製品番号: HY-161883
CAS 番号: 3036530-41-0
研究分野:  

Cancer

JP-2-249 is a molecular glue that acts as a potent degrader of SMARCA2. JP-2-249 shows decreasing protein level of SMARCA2 in MV-4-11 cells at 1-10 μM .
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製品番号: HY-180910
Target:  

SARS-CoV Virus Protease

研究分野:  

Infection

SARS-CoV-2 Mpro-IN-53 (Compound 7) is a SARS-CoV-2 M pro inhibitor. SARS-CoV-2 Mpro-IN-53 causes a decrease in M pro radius of gyration .
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製品番号: HY-183138
CAS 番号: 86408-45-9
Target:  

Drug Metabolite

研究分野:  

Cardiovascular Disease

N-Demethyldiltiazem is a metabolite of Diltiazem (HY-B0632). N-Demethyldiltiazem increases coronary blood flow, modulates cardiac function, decreases systemic blood pressure and heart rate, and alters papillary muscle developed tension .
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製品番号: HY-B0264
CAS 番号: 93-14-1
別名: Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .
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製品番号: HY-B2105
CAS 番号: 7297-25-8
別名: Tetranitrate; Nitroerythrite
Target:  

Drug Derivative

研究分野:  

Cardiovascular Disease

Erythrityl tetranitrate (Tetranitrate; Nitroerythrite), a nitrate ester, is a long-acting vasodilator with properties similar to nitroglycerin. Erythrityl tetranitrate decreases the counter load of the heart and improvement of the pump function of left ventricle in an acute experiment in case of chronic cardiac insufficiency with stasis .
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