SHR5133
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC50=26.6 nM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2270943-23-0
- 分子式: C19H18F4N6O2
- 分子量:438.38
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
>100 μM
Compound: 22; SHR5133
|
Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
Cytotoxicity against human HepG2.2.15 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer-glo assay
|
[PMID: 35300087] |
化学情報
-
CAS 番号 2270943-23-0
-
分子量 438.38
-
分子式 C19H18F4N6O2
-
SMILES
O=C(C1=C2CN(C(NC3=CC=C(F)C(C#N)=C3)=O)[C@@H](C)CN2C=N1)N[C@H](C)C(F)(F)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)