Sotolone
Sotolone (Dimethylhydroxyfuranone) is an activator of the human olfactory receptor OR8D1. Sotolone activates the human olfactory receptor OR8D1, with EC50 values of 84.98 μM and 167.2 μM for its S-enantiomer and R-enantiomer, respectively. Sotolone has unique aroma profiles: (R)-sotolone exhibits smoky, burnt, herbal and grassy notes; (S)-sotolone presents sweet, milky, sour and nutty notes. Sotolone also acts as an antifungal agent, showing moderate inhibitory activity against Magnaporthe oryzae in vitro.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: ≥95.0%
- CAS 番号: 28664-35-9
- 分子式: C6H8O3
- 分子量:128.13
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Sotolone (200 µg/mL; 2-6 days) exhibits weak to moderate in vitro inhibitory activity against Magnaporthe oryzae BV, Sclerotium rolfsii, and Phytophthora capsici, with IC50 values of 256.0 µg/mL, 333.7 µg/mL, and 279.2 µg/mL respectively, and weaker activity against other tested phytopathogenic fungi[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 28664-35-9
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性状 Liquid (Density: 1.049 g/cm3)
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分子量 128.13
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分子式 C6H8O3
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Color Colorless to light yellow
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SMILES
O=C1OC(C(=C1O)C)C
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別名
Dimethylhydroxyfuranone
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (780.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8046 mL | 39.0229 mL | 78.0457 mL | 195.1143 mL |
| 5 mM | 1.5609 mL | 7.8046 mL | 15.6091 mL | 39.0229 mL | |
| 10 mM | 0.7805 mL | 3.9023 mL | 7.8046 mL | 19.5114 mL | |
| 15 mM | 0.5203 mL | 2.6015 mL | 5.2030 mL | 13.0076 mL | |
| 20 mM | 0.3902 mL | 1.9511 mL | 3.9023 mL | 9.7557 mL | |
| 25 mM | 0.3122 mL | 1.5609 mL | 3.1218 mL | 7.8046 mL | |
| 30 mM | 0.2602 mL | 1.3008 mL | 2.6015 mL | 6.5038 mL | |
| 40 mM | 0.1951 mL | 0.9756 mL | 1.9511 mL | 4.8779 mL | |
| 50 mM | 0.1561 mL | 0.7805 mL | 1.5609 mL | 3.9023 mL | |
| 60 mM | 0.1301 mL | 0.6504 mL | 1.3008 mL | 3.2519 mL | |
| 80 mM | 0.0976 mL | 0.4878 mL | 0.9756 mL | 2.4389 mL | |
| 100 mM | 0.0780 mL | 0.3902 mL | 0.7805 mL | 1.9511 mL |
Sotolone 関連分類
HY-W021008 関連分類
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