SPR41
SPR41 is a potent SARS-CoV-2 main protease inhibitor with Ki values of 0.184, 0.252, 14.4 µM for SARS-CoV-2 Mpro, hCatL, hCatB, respectively. SPR41 shows antiviral and cytotoxicity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C27H37N3O5
- 分子量:483.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Ki: 0.184 µM (SARS-CoV-2 Mpro); 0.252 µM (hCatL); 14.4 µM (hCatB)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
14.5 μM
Compound: SPR41
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Cytotoxicity against human Huh-7 cells overexpressing human ACE2 assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human Huh-7 cells overexpressing human ACE2 assessed as reduction in cell viability incubated for 24 hrs by MTT assay
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[PMID: 36549112] |
化学情報
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分子量 483.60
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分子式 C27H37N3O5
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SMILES
O=C(OCC1=CC=CC=C1)N[C@@H](CC2CCCCC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SPR41 関連分類
HY-152224 関連分類
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