ST638
ST638 is a potent tyrosine kinase inhibitor (IC50=370 nM). ST638 also targets the CSF-1 receptor and inhibits PGE2 production.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 107761-24-0
- 分子式: C19H18N2O3S
- 分子量:354.42
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-108611
AACOCF3cPLA2 Inhibitor -
HY-13402
VarespladibsPLA2 Inhibitor -
HY-100736
ML348APT1/LYPLA1 Inhibitor -
HY-100737
ML349APT2/LYPLA2 Inhibitor -
HY-13525
CP-91149Glycogen Phosphorylase Inhibitor -
HY-19619
m-3M3FBSPhospholipase C Activator -
HY-18570
1-Naphthaleneacetic acidPhospholipase Inhibitor -
HY-18570B
1-Naphthaleneacetic acid,suitable for plant cell culturePlant Growth Hormone -
HY-108615
CP-316819Glycogen Phosphorylase Inhibitor -
HY-107411
Bromoenol lactonePhospholipase Inhibitor -
HY-115062
MJ33 lithium saltPLA2 Inhibitor -
HY-123070
ONO-RS-082PLA2 Inhibitor
生物活性
製品説明
化学情報
-
CAS 番号 107761-24-0
-
分子量 354.42
-
分子式 C19H18N2O3S
-
SMILES
O=C(N)/C(C#N)=C/C1=CC(CSC2=CC=CC=C2)=C(O)C(OCC)=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
参考文献
[1]. Puri J, et al. Selective inhibition of PGE2 production in cells transfected with c-fms encoded CSF-1 receptor genes by the tyrosine kinase inhibitor, ST638. Agents Actions. 1991 Jul;33(3-4):314-7. [Content Brief]
[2]. Fuortes M, et al. Adhesion-dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J Cell Biol. 1993 Feb;120(3):777-84. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
ST638 関連分類
HY-112446 関連分類
Powered by Bioz