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United States

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製品番号: HY-183875

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TMPBM ligand-1

TMPBM ligand-1 (compound d9A1 warhead) is an SLC9A1 ligand. TMPBM ligand-1 can be used for the synthesis of d9A1-2 (HY-183892). TMPBM ligand-1 is applicable to research on cancers such as chronic myeloid leukemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2640254-08-4
分子式: C₂₃H₂₄FN₃O₂
分子量:393.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

TMPBM ligand-1 構造式

CAS 番号: 2640254-08-4

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

SLC9A1

体外実験

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2640254-08-4
分子量 393.45
分子式 C₂₃H₂₄FN₃O₂
SMILES

O=C(O)C1=CC=C(C2=CC=C(F)C(C)=C2)C(N3CCC(C4=C(C)N=CN4)CC3)=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Ariel Bensimon, et al. Compounds for targeted degradation of carrier proteins and uses thereof. EP3808741A1. EPO. 2021-04-21.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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