TPN729
TPN729 is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2.28 nM. TPN729 affects erectile function and it can be used for the research of erectile dysfunction.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 936951-20-1
- 分子式: C25H36N6O4S
- 分子量:516.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PDE5 2.28 nM (IC50) |
PDE6 45.2 nM (IC50) |
PDE1 566 nM (IC50) |
PDE4 834 nM (IC50) |
PDE11 6090 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats with corpora cavernosa complete exposure[1]
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Dosage:1.25, 2.5 and 5.0 mg/kg
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Administration:Intraduodenal (i.d.) injection; 1.25, 2.5 and 5.0 mg/kg, once
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Result:Dose-dependently increased the maximum intracavernous pressure (ICP) and ICP/blood pressure (BP).
化学情報
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CAS 番号 936951-20-1
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分子量 516.66
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分子式 C25H36N6O4S
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SMILES
O=S(C1=CC=C(OCCC)C(C(NC2=C3N(C)N=C2CCC)=NC3=O)=C1)(N(C)CCN4CCCC4)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
TPN729 関連分類
HY-116808 関連分類
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