トランスフェリン
Based on 3 publication(s) in Google Scholar
Holo-Bovine Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Holo-Bovine Transferrin can bind to and mediate the transport of iron.
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- 純度: 99.0%
- CAS 番号: 11096-37-0
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Holo-Bovine Transferrin
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生物活性
Transferrin receptor[1]
Holo-Bovine Transferrin (0.2, 1 and 5 μM, 30 min) enhances the enzymatic activity of thrombin[2]. Transferrins (0.2, 1 and 5 μM, 30 min) enhances the ability of thrombin and FXIIa to hydrolyze their natural substrates (fibrinogen)[2]. Transferrins can conjugate with cytochrome c, the conjugates can be uptaken by transferrin receptor overexpressing A549 cells, thereby inducing cell death[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 11096-37-0
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性状 Solid
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Color Brown to reddish brown
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SMILES
[Holo-Bovine Transferrin]
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別名
Transferrins
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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EBioMedicine
Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy. [Abstract]2024 Jul 1:105:105212. PMID: 38954976 -
Adv Healthc Mater
2025 Apr;14(9):e2404388. PMID: 40018834 -
Biochem Pharmacol
Targeted degradation of CD24 by a transferrin receptor-engaging bispecific degrader enhances antitumor immunity. [Abstract]2026 Apr:246:117721. PMID: 41558617
溶剤 & 溶解度
H2O : 100 mg/mL (Need ultrasonic)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Li H, et al. Transferrin/transferrin receptor-mediated drug delivery. Med Res Rev. 2002 May;22(3):225-50. [Content Brief]
[2]. Tang X, et al. Transferrin plays a central role in coagulation balance by interacting with clotting factors. Cell Res. 2020 Feb;30(2):119-132. [Content Brief]
[3]. Saxena M, et al. Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate. PLoS One. 2018 Apr 12;13(4):e0195542. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Holo-Bovine Transferrin 関連分類
HY-P3267 関連分類
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