Tricalcium phosphate
Based on 1 Customer Validation
Tricalcium phosphate is a calcium-phosphorus compound mainly composed of calcium ions and phosphate (PO43-). Tricalcium phosphate promotes osteogenic differentiation, inhibits adipogenic and chondrogenic differentiation, and serves as a scaffold for spinal fusion implants. Tricalcium phosphate supports reparative dentin formation, mineralized nodule formation, and calcium ion release. Tricalcium phosphate is commonly used in fields such as biomaterials, bone repair, food additives, and pharmaceutical preparations.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.00%
- CAS 番号: 7758-87-4
- 分子式: Ca3(PO4)2
- 分子量:310.18
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-W243408D
Calcium carbonate, for cell culture -
HY-21170B
Trifluoromethanesulfonate lithium -
HY-B2242
Calcium phosphate -
HY-Y1054
Magnesium stearate -
HY-W011727A
Pyridoxal 5'-phosphate monohydrate -
HY-Y0332B
Potassium dihydrogen phosphate, AR,99.5% -
HY-Y0332K
Potassium dihydrogen phosphate, for cell culture -
HY-Y0308E
Sodium phosphate dibasic, for cell culture -
HY-Y1267D
Magnesium sulfate, for cell culture -
HY-Y1267
Magnesium sulfate -
HY-Y0308
Disodium phosphate
生物活性
製品説明
体外実験
Tricalcium phosphate (5 mg/mL; 8-25 days) increase ALP activity, a marker of osteogenic differentiation, in hBMSCs by 1.4-fold after 8 days and 2.2-fold after 25 days[2].
Tricalcium phosphate (5 mg/mL; 8 days) induce osteogenic gene expression in hBMSCs, increasing Runx2 by 2.3-fold and BMP2 by 4.7-fold after 8 days[2].
Tricalcium phosphate (10-20%; 4, 7, 10 days) conditioned medium from light-cured composites causes human dental pulp stem cells to exhibit comparable mineralized nodule formation to each other, with lower mineralization than controls under differentiation conditions on day 10[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
Tricalcium phosphate (5 mg/mL; added to hBMSC culture media; 8 days; surgically implanted; single administration) scaffold combined with untreated hBMSCs supports spinal fusion in immunodeficient rats, achieving 75% fusion with 0.5% bone surface area in fusion mass after 8 weeks[2].
Tricalcium phosphate (10%; local application; light-cured for 40 s) resolves pulp inflammation by week 3 and supports moderate to abundant mineralized tissue formation by weeks 3 and 6, respectively, in Wistar rats with exposed dental pulp[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 7758-87-4
-
性状 Solid
-
分子量 310.18
-
分子式 Ca3(PO4)2
-
Color White to off-white
-
SMILES
[Ca3(PO4)2]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
-
データシート (281 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tricalcium phosphate 関連分類
HY-D0833 関連分類
Powered by Bioz