Tyrocidine A
Tyrocidine A is an amphipathic cyclic decapeptide natural product, as well as a membrane-disrupting agent and an antibacterial agent. Tyrocidine A exhibits moderate activity against Gram-positive bacteria. Tyrocidine A can insert into bacterial cell membranes, form porous channels, disrupt membrane integrity and induce bacterial cell death. Tyrocidine A can be used in studies related to bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1481-70-5
- 分子式: C66H87N13O13
- 分子量:1270.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Tyrocidine A (overnight treatment) exhibits moderate antibacterial activity against Gram-positive strains (MIC 16-32 μg/mL) at a calcium ion concentration of 25 mg/L, while it shows no activity against Gram-negative E. coli ATCC 25922 (MIC >128 μg/mL); its activity decreases moderately at a calcium ion concentration of 50 mg/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1481-70-5
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分子量 1270.48
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分子式 C66H87N13O13
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SMILES
O=C1N2[C@](CCC2)([H])C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1CC3=CC=CC=C3)=O)CC(C)C)=O)CCCN)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)CCC(N)=O)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC6=CC=CC=C6)=O
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配列
cyclo(Asn-Gln-Tyr-Val-Orn-Leu-DPhe-Pro-Phe-DPhe)
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シーケンスの短縮
cyclo(NQYV-Orn-L-DPhe-PF-DPhe)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tyrocidine A 関連分類
HY-P11889 関連分類
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