Umirolimus-d5
Based on 1 Customer Validation
Umirolimus-d5 is the deuterium labeled Umirolimus (HY-122402). Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.96%
- 分子式: C55H82D5NO14
- 分子量:991.31
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 851536-75-9
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性状 Solid
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分子量 991.31
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分子式 C55H82D5NO14
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Color White to off-white
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SMILES
O=C1N2[C@](CCCC2)([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C([C@H](C[C@@]3([H])O[C@@](C1=O)([C@@H](CC3)C)O)OC)\C)C)C)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H]4C[C@H]([C@@H](CC4)OCCOC([2H])([2H])C([2H])([2H])[2H])OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (100.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0088 mL | 5.0438 mL | 10.0877 mL | 25.2192 mL |
| 5 mM | 0.2018 mL | 1.0088 mL | 2.0175 mL | 5.0438 mL | |
| 10 mM | 0.1009 mL | 0.5044 mL | 1.0088 mL | 2.5219 mL | |
| 15 mM | 0.0673 mL | 0.3363 mL | 0.6725 mL | 1.6813 mL | |
| 20 mM | 0.0504 mL | 0.2522 mL | 0.5044 mL | 1.2610 mL | |
| 25 mM | 0.0404 mL | 0.2018 mL | 0.4035 mL | 1.0088 mL | |
| 30 mM | 0.0336 mL | 0.1681 mL | 0.3363 mL | 0.8406 mL | |
| 40 mM | 0.0252 mL | 0.1261 mL | 0.2522 mL | 0.6305 mL | |
| 50 mM | 0.0202 mL | 0.1009 mL | 0.2018 mL | 0.5044 mL | |
| 60 mM | 0.0168 mL | 0.0841 mL | 0.1681 mL | 0.4203 mL | |
| 80 mM | 0.0126 mL | 0.0630 mL | 0.1261 mL | 0.3152 mL | |
| 100 mM | 0.0101 mL | 0.0504 mL | 0.1009 mL | 0.2522 mL |