UR-MB108
UR-MB108 is a selective ABCG2 inhibitor with an IC50 value of 79 nM. UR-MB108 acts as a potent inhibitor of ABCG2 transport and ATPase activity. UR-MB108 can be used in cancer-related research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2412461-98-2
- 分子式: C40H38N6O4
- 分子量:666.77
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: 79 nM (ABCG2 (BCRP))[1]
UR-MB108 potently inhibits ABCG2-mediated Hoechst 33342 efflux in MCF-7/Topo cells with an IC50 of 79 nM and a maximal inhibitory effect of 91%, and shows no inhibitory activity against ABCB1 or ABCC1 transporters[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2412461-98-2
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分子量 666.77
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分子式 C40H38N6O4
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SMILES
CCC(C1=CC=C(C=C1NC(C2=NC3=C(C=C2)C=CC=C3)=O)C4=CN(N=N4)C5=CC=C(C=C5)CCN6CCC7=C(C6)C=C(C(OC)=C7)OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UR-MB108 関連分類
HY-146676 関連分類
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