Ursonic acid methyl ester
Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED50 values of >100 µg/ml.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 989-72-0
- 分子式: C31H48O3
- 分子量:468.71
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 518A2 | EC50 |
1.24 μM
Compound: 7
|
Cytotoxicity against human 518A2 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human 518A2 cells assessed as cell survival after 96 hrs by SRB assay
|
[PMID: 26177446] |
| 8505C | EC50 |
1.56 μM
Compound: 7
|
Cytotoxicity against human 8505C cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human 8505C cells assessed as cell survival after 96 hrs by SRB assay
|
[PMID: 26177446] |
| A549 | EC50 |
1.64 μM
Compound: 7
|
Cytotoxicity against human A549 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as cell survival after 96 hrs by SRB assay
|
[PMID: 26177446] |
| HepG2 | CC50 |
>400 μM
Compound: 5a
|
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 29326018] |
| HT-29 | EC50 |
1.15 μM
Compound: 7
|
Cytotoxicity against human HT-29 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human HT-29 cells assessed as cell survival after 96 hrs by SRB assay
|
[PMID: 26177446] |
| MCF7 | EC50 |
1.3 μM
Compound: 7
|
Cytotoxicity against human MCF7 cells assessed as cell survival after 96 hrs by SRB assay
Cytotoxicity against human MCF7 cells assessed as cell survival after 96 hrs by SRB assay
|
[PMID: 26177446] |
| NTUB1 | IC50 |
29.57 μM
Compound: 19
|
Cytotoxicity against human NTUB1 cells after 72 hrs by MTT assay
Cytotoxicity against human NTUB1 cells after 72 hrs by MTT assay
|
[PMID: 19758808] |
| Vero | CC50 |
>400 μM
Compound: 5a
|
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
|
[PMID: 29326018] |
化学情報
-
CAS 番号 989-72-0
-
分子量 468.71
-
分子式 C31H48O3
-
SMILES
CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(OC)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)