Varsetatug
Based on 1 Customer Validation
Varsetatug (CX-2051 antibody) is a humanized IgG1κ monoclonal antibody inhibitor targeting EpCAM/TROP1/CD326. Varsetatug serves as the antibody component of the ADC compound CX-2051. It can be used in research on cancers including breast cancer, prostate cancer and ovarian cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97%
- CAS 番号: 3036004-28-8
- 分子量:155.116 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Human IgG1 kappa
Human
EpCAM/TROP1/CD326
CX-2051 is a masked EpCAM antibody-drug conjugate (ADC) carrying a novel camptothecin-based topoisomerase I (Topo-I) payload, a linker, and an EpCAM-targeting antibody moiety (Varsetatug).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Loaded Varsetatug on ProA biosensor, can bind EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P72367) with an affinity constant of 1.693E-07 M as determined in BLI assay.
化学情報
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CAS 番号 3036004-28-8
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性状 Liquid
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分子量 155.116 kDa
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Color Colorless to light yellow
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SMILES
N/A
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別名
CX-2051 antibody
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)