Viroxime
Viroxime is an antiviral agent.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 63198-97-0
- 分子式: C17H18N4O3S
- 分子量:358.41
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BSC-1 | IC50 |
0.02 μg/mL
Compound: 1
|
Antiviral activity against Poliovirus (PV-1) using plaque reduction assay using BSC1 cells
Antiviral activity against Poliovirus (PV-1) using plaque reduction assay using BSC1 cells
|
[PMID: 9341923] |
| CV-1 | ED50 |
275 μg/mL
Compound: Enviroxime2
|
Compound was evaluated for chemotherapeutic index in CV-1 cells (chemotherapeutic index=50% cytotoxic dose/50% effective dose)
Compound was evaluated for chemotherapeutic index in CV-1 cells (chemotherapeutic index=50% cytotoxic dose/50% effective dose)
|
[PMID: 3005577] |
| CV-1 | ED50 |
8.8 μg/mL
Compound: Enviroxime2
|
Antiviral activity against poliovirus type 1 in CV-1 cells
Antiviral activity against poliovirus type 1 in CV-1 cells
|
[PMID: 3005577] |
| H1-HeLa | CC50 |
9.9 μM
Compound: Enviroxime
|
Cytotoxicity against human H1-HeLa cells infected with 1 MOI human rhinovirus 14 pretreated with compound for 1 hr followed by viral infection measured by MTT assay
Cytotoxicity against human H1-HeLa cells infected with 1 MOI human rhinovirus 14 pretreated with compound for 1 hr followed by viral infection measured by MTT assay
|
[PMID: 38389877] |
| H1-HeLa | IC50 |
41 μM
Compound: Enviroxime
|
Cytotoxicity against human H1-HeLa cells transfected with EV71 replicon measured after 8 hrs by MTT assay
Cytotoxicity against human H1-HeLa cells transfected with EV71 replicon measured after 8 hrs by MTT assay
|
[PMID: 38389877] |
| HeLa | ED50 |
5.1 μg/mL
Compound: Enviroxime2
|
Antiviral activity against rhinovirus type 10 in Hela cells
Antiviral activity against rhinovirus type 10 in Hela cells
|
[PMID: 3005577] |
| HeLa | IC50 |
0.04 μg/mL
Compound: 1
|
Antiviral activity against Rhinovirus (RV-14) in HeLa cells using CPE/XTT assay
Antiviral activity against Rhinovirus (RV-14) in HeLa cells using CPE/XTT assay
|
[PMID: 9341923] |
| HeLa | IC50 |
0.04 μg/mL
Compound: 1
|
Antiviral activity against Rhinovirus (RV-16) in HeLa cells using CPE/XTT assay
Antiviral activity against Rhinovirus (RV-16) in HeLa cells using CPE/XTT assay
|
[PMID: 9341923] |
| HeLa | IC50 |
0.05 μg/mL
Compound: 1
|
Antiviral activity against Coxsackie virus (CoxA21) in HeLa cells using CPE/XTT assay
Antiviral activity against Coxsackie virus (CoxA21) in HeLa cells using CPE/XTT assay
|
[PMID: 9341923] |
| HeLa | IC50 |
0.06 μg/mL
Compound: 1
|
Antiviral activity against Poliovirus (PV-1) in HeLa cells using CPE/XTT assay
Antiviral activity against Poliovirus (PV-1) in HeLa cells using CPE/XTT assay
|
[PMID: 9341923] |
| HeLa | IC50 |
0.07 μg/mL
Compound: 1
|
Antiviral activity against Rhinovirus (RV-2) in HeLa cells using CPE/XTT assay
Antiviral activity against Rhinovirus (RV-2) in HeLa cells using CPE/XTT assay
|
[PMID: 9341923] |
| Huh-7 | CC50 |
25 μM
Compound: 93
|
Cytotoxicity against human Huh-7 cells
Cytotoxicity against human Huh-7 cells
|
[PMID: 33539089] |
| KB | CC50 |
2 μg/mL
Compound: Enviroxime
|
Cellular toxicity in KB cells
Cellular toxicity in KB cells
|
[PMID: 12852746] |
| RD | CC50 |
>223.21 μM
Compound: 1
|
Cytotoxicity against human RD cells assessed as reduction in cell viability after 24 to 36 hrs by MTS-based CPE reduction assay
Cytotoxicity against human RD cells assessed as reduction in cell viability after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| RD | CC50 |
1.5 μM
Compound: Enviroxime
|
Cytotoxicity against human RD cells by neutral red uptake assay
Cytotoxicity against human RD cells by neutral red uptake assay
|
[PMID: 33031923] |
| RD | CC50 |
10 μM
Compound: Enviroxime
|
Cytotoxicity against human RD cells assessed as reduction in cell viability by visual analysis
Cytotoxicity against human RD cells assessed as reduction in cell viability by visual analysis
|
[PMID: 37120998] |
| RD | CC50 |
28 μM
Compound: Enviroxime
|
Cytotoxicity against human RD cells infected with Enterovirus A71 assessed as reduction in cell viability measured by CCK-8 assay
Cytotoxicity against human RD cells infected with Enterovirus A71 assessed as reduction in cell viability measured by CCK-8 assay
|
[PMID: 32619885] |
| RD | CC50 |
4.2 μM
Compound: Enviroxime
|
Cytotoxicity against human RD cells by microscopic based visual inspection method
Cytotoxicity against human RD cells by microscopic based visual inspection method
|
[PMID: 33031923] |
| RD | CC50 |
5.5 μM
Compound: Enviroxime
|
Cytotoxicity against human RD cells assessed as reduction in cell viability by neutral red dye based spectrophotometric analysis
Cytotoxicity against human RD cells assessed as reduction in cell viability by neutral red dye based spectrophotometric analysis
|
[PMID: 37120998] |
| RD | EC50 |
0.24 μM
Compound: 1
|
Antiviral activity against Enterovirus 71 infected in human RD cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Enterovirus 71 infected in human RD cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | CC50 |
>100 μM
Compound: 2
|
Cytotoxicity against African green monkey Vero cells after 3 days by spectrophotometry based MTS/PMS assay
Cytotoxicity against African green monkey Vero cells after 3 days by spectrophotometry based MTS/PMS assay
|
[PMID: 22305341] |
| Vero | CC50 |
>100 μM
Compound: 59
|
Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
|
[PMID: 19924996] |
| Vero | CC50 |
>223.21 μM
Compound: 1
|
Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability after 24 to 36 hrs by MTS-based CPE reduction assay
Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
>186 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B4 infected in african green monkey Vero cells by after 24 to 36 hrs MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B4 infected in african green monkey Vero cells by after 24 to 36 hrs MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
0.026 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 2 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 2 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.027 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 41 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 41 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.027 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 63 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 63 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.028 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 39 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 39 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.029 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 29 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 29 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.033 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 85 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 85 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.038 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 9 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 9 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.04 μM
Compound: Enviroxime
|
Antiviral activity against Human poliovirus 3 strain Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human poliovirus 3 strain Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.042 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 15 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 15 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.06 μM
Compound: Enviroxime
|
Antiviral activity against Human poliovirus 2 Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human poliovirus 2 Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.1 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B6 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B6 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
0.1 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 89 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 89 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.11 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 14 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 14 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.11 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 42 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 42 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.11 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 70 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 70 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.12 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B5 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B5 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
0.12 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus A16 (strain G-10) A16 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus A16 (strain G-10) A16 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.14 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 86 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 86 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.15 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B2 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B2 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
0.15 μM
Compound: 1
|
Antiviral activity against Human enterovirus 71 infected in monkey African green Vero cells by MTS-based CPE reduction assay
Antiviral activity against Human enterovirus 71 infected in monkey African green Vero cells by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
0.15 μM
Compound: Enviroxime
|
Antiviral activity against Human enterovirus 71 (strain BRCR) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human enterovirus 71 (strain BRCR) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.19 μM
Compound: Enviroxime
|
Antiviral activity against Human poliovirus 1 strain Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human poliovirus 1 strain Sabin infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.25 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 45 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 45 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.48 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus A21 (strain Coe) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus A21 (strain Coe) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.5 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus B3 harboring wild type nonstructural protein 3A infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
Antiviral activity against Human coxsackievirus B3 harboring wild type nonstructural protein 3A infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.7 μM
Compound: 2
|
Antiviral activity against Coxsackievirus B3 Nancy infected in african green monkey Vero cells assessed as inhibition of virus-induced cell death after 3 days by spectrophotometry based MTS/PMS assay
Antiviral activity against Coxsackievirus B3 Nancy infected in african green monkey Vero cells assessed as inhibition of virus-induced cell death after 3 days by spectrophotometry based MTS/PMS assay
|
[PMID: 22305341] |
| Vero | EC50 |
0.7 μM
Compound: 59
|
Antiviral activity against Coxsackievirus B3 infected in african green monkey Vero cells assessed as reduction of virus-induced cytopathic effect after 3 days by MTS assay
Antiviral activity against Coxsackievirus B3 infected in african green monkey Vero cells assessed as reduction of virus-induced cytopathic effect after 3 days by MTS assay
|
[PMID: 19924996] |
| Vero | EC50 |
0.7 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A I8T mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A I8T mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.72 μM
Compound: Enviroxime
|
Antiviral activity against Human rhinovirus 72 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Human rhinovirus 72 infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
0.75 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B1 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B1 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
| Vero | EC50 |
1.3 μM
Compound: 2
|
Antiviral activity against drug-resistant Coxsackievirus B3 Nancy infected in african green monkey Vero cells assessed as inhibition of virus-induced cell death after 3 days by spectrophotometry based MTS/PMS assay
Antiviral activity against drug-resistant Coxsackievirus B3 Nancy infected in african green monkey Vero cells assessed as inhibition of virus-induced cell death after 3 days by spectrophotometry based MTS/PMS assay
|
[PMID: 22305341] |
| Vero | EC50 |
1.5 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A V45A mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A V45A mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
|
[PMID: 19237651] |
| Vero | EC50 |
1.7 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A H57Y mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A H57Y mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
|
[PMID: 19237651] |
| Vero | EC50 |
1.8 μM
Compound: Enviroxime
|
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A I54F mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
Antiviral activity against Human coxsackievirus B3 harboring nonstructural protein 3A I54F mutant infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by plaque assay
|
[PMID: 19237651] |
| Vero | EC50 |
1.9 μM
Compound: Enviroxime
|
Antiviral activity against Coxsackievirus B3 (strain Nancy) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
Antiviral activity against Coxsackievirus B3 (strain Nancy) infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 3 days by MTS-based CPE reduction assay
|
[PMID: 19237651] |
| Vero | EC50 |
2.48 μM
Compound: 1
|
Antiviral activity against Human coxsackievirus B3 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
Antiviral activity against Human coxsackievirus B3 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
|
[PMID: 26885567] |
化学情報
-
CAS 番号 63198-97-0
-
分子量 358.41
-
分子式 C17H18N4O3S
-
SMILES
O=S(N1C(N)=NC2=C1C=C(/C(C3=CC=CC=C3)=N/O)C=C2)(C(C)C)=O
-
別名
LY 122771-72
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)