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製品番号: HY-W720448

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VR23-d₈

VR23-d₈ is the deuterium labeled VR23 (HY-18741). VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC₅₀=1 nM), chymotrypsin-like proteasomes (IC₅₀=50-100 nM), and caspase-like proteasomes (IC₅₀=3 μM).

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CAS 番号: 2733154-83-9
分子式: C₁₉H₈D₈ClN₅O₆S
分子量:485.93

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (247 KB)

VR23-d₈ 構造式

CAS 番号: 2733154-83-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

アプリケーション

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

化学情報

CAS 番号 2733154-83-9
非標識Cas 1624602-30-7
分子量 485.93
分子式 C₁₉H₈D₈ClN₅O₆S
SMILES

ClC1=CC2=C(C(N3C([2H])(C([2H])(N(C([2H])(C3([2H])[2H])[2H])S(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)(=O)=O)[2H])[2H])=CC=N2)C=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.