VT00065
Based on 1 Customer Validation
VT00065 is a covalent DHS inhibitor. VT00065 forms a redox-dependent covalent bond with the catalytic lysine K329 of DHS, locking the enzyme in an inactive state.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 144163-68-8
- 分子式: C5H8N2S
- 分子量:128.20
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
VT00065 (100 mM; 24 h) covalently and specifically modifies the catalytic K329 residue of purified human DHS, suggesting it acts as a mechanism-based binder with potential to irreversibly inactivate the enzyme, though it exhibits low binding occupancy[1].
VT00065 (2-20 mM; 9 min) exhibits weak, dose-dependent inhibition of deoxyhypusination activity in purified human DHS-eIF5A reactions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 144163-68-8
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性状 Liquid (Density: 1.126±0.06 g/cm3)
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分子量 128.20
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分子式 C5H8N2S
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Color Colorless to light yellow
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SMILES
CNCC1=NC=CS1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
VT00065 関連分類
HY-W141446 関連分類
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