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製品番号: HY-111766

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YD-3

YD-3 is a platelet activation inhibitor. YD-3 inhibits Thrombine-induced rabbit platelets aggregation (IC₅₀: 28.3 μM) and phosphoinositol production. In addition, YD-3 also inhibits Trypsin-induced platelet aggregation in human and rabbit with the IC₅₀ of 38.1 μM and 5.7 μM, respectively, but does not affect the proteolytic activity of trypsin.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 170632-41-4
分子式: C₂₃H₂₀N₂O₂
分子量:356.42

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

YD-3 構造式

CAS 番号: 170632-41-4

容量

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of collagen-induced human platelet aggregation Inhibition of collagen-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of SFLLRN-induced human platelet aggregation Inhibition of SFLLRN-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of thrombin-induced human platelet aggregation Inhibition of thrombin-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	>10 μM Compound: YD-3	Inhibition of U46619-induced human platelet aggregation Inhibition of U46619-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	0.13 μM Compound: YD-3	Inhibition of GYPGKF-induced human platelet aggregation Inhibition of GYPGKF-induced human platelet aggregation	[PMID: 17988878]
Platelet	IC₅₀	164 μM Compound: 11	Inhibition of PAF-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by PAF addition Inhibition of PAF-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by PAF addition	[PMID: 33049608]
Platelet	IC₅₀	184.8 μM Compound: 11	Inhibition of arachidonic acid-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by arachidonic acid addition Inhibition of arachidonic acid-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by arachidonic acid addition	[PMID: 33049608]
Platelet	IC₅₀	212.4 μM Compound: 11	Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by collagen addition Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by collagen addition	[PMID: 33049608]
Platelet	IC₅₀	29.3 μM Compound: 11	Inhibition of thrombin-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by thrombin addition Inhibition of thrombin-induced platelet aggregation in human platelet-rich plasma incubated for 1 min followed by thrombin addition	[PMID: 33049608]

化学情報

CAS 番号 170632-41-4
分子量 356.42
分子式 C₂₃H₂₀N₂O₂
SMILES

O=C(OCC)C1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)C=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zhang Z, et al. Short day promotes gall swelling by a CONSTANS-FLOWERING LOCUS T pathway in Zizania latifolia. Plant J. 2024 Nov;120(3):1014-1031. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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