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製品番号: HY-W665208

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Zapotin

Zapotin is a member of the polymethoxyflavones, which are natural polyphenols from the group of flavonoid. Zapotin exhibits antidepressant, anticancer, antifungal, and antioxidant activity. Zapotin is a chemopreventive and chemotherapeutic agent. Zapotin can result in a reduction of large aberrant crypt foci in CF-1 mouse model. Zapotin inhibits autophagosome formation. Zapotin has inhibitory activity in mouse mammary organ culture with an IC₅₀ of 50 µg/mL.

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CAS 番号: 14813-19-5
分子式: C₁₉H₁₈O₆
分子量:342.34

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Zapotin 構造式

CAS 番号: 14813-19-5

容量

価格（税別）

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数量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	7.6 μM Compound: 1, zapotin	Inhibition of TPA-induced NF-kappaB activity in HepG2 cells Inhibition of TPA-induced NF-kappaB activity in HepG2 cells	[PMID: 17228877]
HL-60	ED₅₀	0.5 μM Compound: 1, zapotin	Induction of differentiation in human HL60 cell line Induction of differentiation in human HL60 cell line	[PMID: 17228877]
T-24	IC₅₀	3.4 μM Compound: 1, zapotin	Inhibition of TPA-induced ODC activity in T24 cells Inhibition of TPA-induced ODC activity in T24 cells	[PMID: 17228877]

化学情報

CAS 番号 14813-19-5
分子量 342.34
分子式 C₁₉H₁₈O₆
SMILES

COC1=CC=C2OC(C3=C(C=CC=C3OC)OC)=CC(C2=C1OC)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Strawa, J. W., et al., (2021). Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International journal of molecular sciences, 22(24), 13227. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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