2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. JZY3221

JZY3221 is an androgen receptor (AR) inhibitor. JZY3221 binds to the AR ligand-binding domain to inhibit AR function. JZY3221 constitutes the AR inhibitory moiety of DALTAC JZY3032 (HY-184124). JZY3221 is applicable to research related to prostate cancer.

For research use only. We do not sell to patients.

JZY3221

JZY3221 Chemical Structure

Size Price Stock Quantity
5 mg Get quote 6 - 8 weeks 5 - 7 weeks 7 - 9 weeks 5 - 7 weeks
10 mg Get quote 6 - 8 weeks 5 - 7 weeks 7 - 9 weeks 5 - 7 weeks
25 mg Get quote 6 - 8 weeks 5 - 7 weeks 7 - 9 weeks 5 - 7 weeks
50 mg Get quote 6 - 8 weeks 5 - 7 weeks 7 - 9 weeks 5 - 7 weeks
100 mg   Get quote  
200 mg   Get quote  
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JZY3221 Related Antibodies

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Description

JZY3221 is an androgen receptor (AR) inhibitor. JZY3221 binds to the AR ligand-binding domain to inhibit AR function. JZY3221 constitutes the AR inhibitory moiety of DALTAC JZY3032 (HY-184124). JZY3221 is applicable to research related to prostate cancer[1].

In Vitro

JZY3221 exhibits only limited cell growth inhibitory activity in AR-positive 22Rv1 prostate cancer cells[1].
JZY3221 directly binds to purified AR protein[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

JZY3221 Related Antibodies
Molecular Weight

369.85

Formula

C19H20ClN5O
SMILES

ClC1=CC(N(C)[C@H](CC2)CC[C@@H]2NC(C3=NN=CC=C3)=O)=CC=C1C#N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JZY3221 Related Classifications

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  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JZY3221JZY 3221JZY-3221Androgen ReceptorAR-positive prostate cancer cellspurified AR proteinprostate cancerandrogen receptorAR ligand-binding domain22Rv1 prostate cancer cellspurified androgen receptor proteinInhibitorinhibitorinhibit

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JZY3221
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HY-184126
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