Ki 23057
Ki 23057 is a competitive, orally active inhibitor for tyrosine kinase, which inhibits the phosphorylation of K-samII/FGF-R2, VEGF-R1, VEGF-R2, PDGF-Rβ and c-Kit, with IC50s of 88, 69, 83, 100 and 480 nM. Ki 23057 inhibits the proliferation of sclerogastric cancer cells OCUM-2MD3 and OCUM-8, and induces apoptosis. Ki 23057 exhibits antitumor efficacy in mouse models.
For research use only. We do not sell to patients.
- CAS No.: 516523-31-2
- Formula: C30H35N3O4
- Molecular Weight:501.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 516523-31-2
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Molecular Weight 501.62
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Formula C30H35N3O4
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SMILES
COC1=C(OCCNCCO)C=C2N=CC=C(OC3=CC=C(NC4=CC=C(C(C)(C)C)C=C4)C=C3)C2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)