2-Chlorophenothiazine
Based on 1 Customer Validation
2-Chlorophenothiazine is a phenothiazine derivative. 2-Chlorophenothiazine has the activity of inhibiting DNA, RNA and protein synthesis. 2-Chlorophenothiazine is an intermediate in the synthesis of Chlorpromazine (HY-12708) and Perphenazine (HY-A0077).
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- CAS No.: 92-39-7
- 화학식: C12H8ClNS
- 분자량:233.72
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보관:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-Y1749R
2-Chlorophenothiazine (Standard)Drug Intermediate -
HY-W012258
2-MethoxyphenothiazineBiochemical Assay Reagent -
HY-W011996
2-Methylthiophenothiazine -
HY-W012258R
2-Methoxyphenothiazine (Standard)Biochemical Assay Reagent -
HY-W008601
Trazodone impurity 5 hydrochlorideDrug Impurity -
HY-W010593
EthylenethioureaTumorigenic Agent -
HY-W015626
2,5-DichloropyridineBiochemical Reagent -
HY-W008601R
Trazodone impurity 5 hydrochloride (Standard) -
HY-W010593R
Ethylenethiourea (Standard)Tumorigenic Agent
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
>100 μM
Compound: 14
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Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
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[PMID: 21563750] |
Chemical Information
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CAS No. 92-39-7
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Appearance Solid
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분자량 233.72
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화학식 C12H8ClNS
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SMILES
ClC(C=C1N2)=CC=C1SC3=C2C=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
용액&용해도
In Vitro:
DMSO : 25 mg/mL (106.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2786 mL | 21.3931 mL | 42.7862 mL | 106.9656 mL |
| 5 mM | 0.8557 mL | 4.2786 mL | 8.5572 mL | 21.3931 mL | |
| 10 mM | 0.4279 mL | 2.1393 mL | 4.2786 mL | 10.6966 mL | |
| 15 mM | 0.2852 mL | 1.4262 mL | 2.8524 mL | 7.1310 mL | |
| 20 mM | 0.2139 mL | 1.0697 mL | 2.1393 mL | 5.3483 mL | |
| 25 mM | 0.1711 mL | 0.8557 mL | 1.7114 mL | 4.2786 mL | |
| 30 mM | 0.1426 mL | 0.7131 mL | 1.4262 mL | 3.5655 mL | |
| 40 mM | 0.1070 mL | 0.5348 mL | 1.0697 mL | 2.6741 mL | |
| 50 mM | 0.0856 mL | 0.4279 mL | 0.8557 mL | 2.1393 mL | |
| 60 mM | 0.0713 mL | 0.3566 mL | 0.7131 mL | 1.7828 mL | |
| 80 mM | 0.0535 mL | 0.2674 mL | 0.5348 mL | 1.3371 mL | |
| 100 mM | 0.0428 mL | 0.2139 mL | 0.4279 mL | 1.0697 mL |
2-Chlorophenothiazine Related Classifications
HY-Y1749 Related Classifications
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